- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB, ICC/IF, IP, FC
- 特异性:Human
Anti-Cleaved PARP (Asp214) Rabbit antibody
产品详情
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产品名称
Anti-Cleaved PARP (Asp214) Rabbit antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Cleaved PARP (Asp214) Rabbit polyclonal antibody
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抗体应用
WB, ICC/IF, IP, FC
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应用推荐
WB: 1/500-1/2000
ICC/IF: 1/50-1/200
IP: 1/50
FC: 1/50
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特异性
Human
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制备方法
Antigen: A synthesized peptide derived from human Cleaved PARP
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组分
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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储存方法
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P09874.Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150.
相关服务
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