重组人CTSA蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human CTSA/PPGB Ala29-Tyr480 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

PPGB

cathepsin A(CTSA)

Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.

Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Store at <-20°C, minimize freeze-thaw cycles.