重组小鼠SFN蛋白

产品详情

  • 产品名称
    重组小鼠SFN蛋白
  • 蛋白种属
    小鼠
  • 表达宿主
    大肠杆菌
  • Unitprot ID
  • 克隆构建
    A DNA sequence encoding the mouse SFN (NP_061224.2) (Met 1-Ser 248) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminu.
  • 蛋白纯度
    > 95 % as determined by SDS-PAGE
  • 分子量
    The recombinant mouse SFN consists of 250 amino acids and has a calculated molecular mass of 27.7 kDa. It migrates as an approximately 32 kDa band in SDS-PAGE under reducing conditions.
  • 蛋白别名
    14-3-3 SIGMA; ER; RP23-137L22.11; MME1; STRATIFIN; YWHAS
  • 蛋白全名
    14-3-3 protein sigma
  • 蛋白描述
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
  • 发货形式
    Lyophilized from sterile 50mM Tris, 150mM NaCl, pH 8.0
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    Please contact us for more information.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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