- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IP
- 特异性:Human, Mouse, Rat; other species not tested.
产品详情
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产品名称
ACTA2/smooth muscle actin antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
ACTA2/smooth muscle actin Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, mouse brown adipose tissue, mouse kidney tissue, mouse liver tissue, mouse skeletal muscle tissue, rat heart tissue. Positive IP detected in mouse heart tissue. Positive IHC detected in human heart tissue, human colon tissue, human skeletal muscle tissue, human small intestine tissue. Observed molecular weight by Western-blot: 42 kDa
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抗体应用
ELISA, WB, IHC, IP
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:200-1:1000
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特异性
Human, Mouse, Rat; other species not tested.
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蛋白别名
a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 specific, Actin, aortic smooth muscle, ACTSA, ACTVS, Alpha actin 2, Alpha SMA, a-SMA, α SMA
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制备方法
This antibody was obtained by immunization of ACTA2/smooth muscle actin recombinant protein (Accession Number: NM_001406463). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
ACTA2 (also known as α-smooth muscle actin or α-SMA) belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 is primarily expressed in vascular smooth muscle and anti-ACTA2 is commonly used to marker smooth muscle cells. This antibody is specific to the ACTA2. It selectively stains the vascular smooth muscle but not cardiac or skeletal muscle.
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参考文献
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- Chen HH, Weng BQ, Cheng KJ, Liu HY, Wang SQ, Lu YY. Effect of the vascular endothelial growth factor expression level on angiopoietin-2-mediated nasopharyngeal carcinoma growth. Vascular cell. 6(1):4. 2014.
- He Y, Wu YT, Huang C. Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis. Biochimica et biophysica acta. 1842(11):2204-15. 2014.
- Liang C, Li X, Zhang L, Cui D, Quan X, Yang W. The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis. Experimental and molecular pathology. 99(2):279-85. 2015.