Anti-Bcl-2 (3H5) Mouse antibody

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  • 抗体类型:单克隆
  • 抗体来源:小鼠
  • 抗体应用:ICC/IF, WB, IHC-P
  • 特异性:Human, Mouse, Rat, Chicken

产品详情

  • 产品名称
    Anti-Bcl-2 (3H5) Mouse antibody
  • 抗体类型
    单克隆
  • 抗体来源
    小鼠
  • 抗体亚型
    小鼠IgG1
  • 抗体描述
    Bcl-2 (3H5) Mouse monoclonal antibody
  • 抗体应用
    ICC/IF, WB, IHC-P
  • 应用推荐

    IF: 1/50-200

    WB: 1/1000-2000

    IHC: 1/200

  • 特异性
    Human, Mouse, Rat, Chicken
  • 制备方法
    Antigen: Synthetic Peptide of Bcl-2
  • 组分
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • 储存方法
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • 背景介绍
    Swiss-Prot Acc.P10415.Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
  • 参考文献
    • Aqueous extract of Fritillariae cirrhosae induces cellular apoptosis through activation of STATs-mediated immunomodulation
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