Anti-BMP-2 antibody

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  • 抗体类型:单克隆
  • 抗体来源:兔
  • 抗体应用:IF, ICC/IF
  • 特异性:Human BMP-2

产品详情

  • 产品名称
    Anti-BMP-2 antibody
  • 抗体类型
    单克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Rabbit monoclonal to BMP-2
  • 抗体应用
    IF, ICC/IF
  • 应用推荐

    ICC/IF: 10-25 μg/mL

  • 特异性
    Human BMP-2
  • 制备方法
    This antibody was obtained from a rabbit immunized with purified, recombinant Human BMP-2 (rh BMP-2; NP_001191.1; Gln283-Arg396).
  • 组分
    0.2 μm filtered solution in PBS with 5% trehalose
  • 储存方法
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • 背景介绍
    BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
  • 参考文献
    • Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6.
    • Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.
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