- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:WB, IHC-P
- 特异性:Human
产品详情
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产品名称
Anti-CDK9 (1C3) Mouse antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
CDK9 (1C3) Mouse monoclonal antibody
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抗体应用
WB, IHC-P
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应用推荐
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
ELISA: 1/10000
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特异性
Human
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制备方法
Antigen: Purified recombinant fragment of human CDK9 expressed in E. Coli.
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组分
Ascitic fluid containing 0.03% sodium azide.
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储存方法
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P50750.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.