Anti-Cleaved-Caspase-3 p12 Rabbit antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB, ICC/IF, FC
  • 特异性:Human, Mouse, Rat

产品详情

  • 产品名称
    Anti-Cleaved-Caspase-3 p12 Rabbit antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Cleaved-Caspase-3 p12 Rabbit polyclonal antibody
  • 抗体应用
    WB, ICC/IF, FC
  • 应用推荐

    WB: 1/1000

    ICC/IF: 1/20

    FC: 1/20

  • 特异性
    Human, Mouse, Rat
  • 蛋白别名
    CPP32; SCA-1; CPP32B
  • 制备方法
    Antigen: Recombinant protein of human Caspase-3 p12
  • 组分
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • 储存方法
    Store at -20°C. Stable for 12 months from date of receipt.
  • 背景介绍
    Swiss-Prot Acc.P42574.Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
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