- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:WB, IHC-P, ICC/IF
- 特异性:Human, Mouse, Rat, Monkey
产品详情
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产品名称
Anti-GRK2 (6C1) Mouse antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
GRK2 (6C1) Mouse monoclonal antibody
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抗体应用
WB, IHC-P, ICC/IF
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应用推荐
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
ICC: 1/200 - 1/1000
ELISA: 1/10000
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特异性
Human, Mouse, Rat, Monkey
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制备方法
Antigen: Purified recombinant fragment of human GRK2 expressed in E. Coli.
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组分
Ascitic fluid containing 0.03% sodium azide.
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储存方法
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P25098.The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes