- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:WB, IHC-P
- 特异性:Human, Rat, Mouse
产品详情
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产品名称
Anti-HP1 alpha (1E8) Mouse antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
HP1 alpha (1E8) Mouse monoclonal antibody
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抗体应用
WB, IHC-P
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应用推荐
WB: 1/500-1;000
IHC: 1/100-200
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特异性
Human, Rat, Mouse
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制备方法
Antigen: Purified recombinant protein expressed in E.coli.
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组分
PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
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储存方法
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P45973.Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.