Anti-HP1 alpha (1E8) Mouse antibody

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  • 抗体类型:单克隆
  • 抗体来源:小鼠
  • 抗体应用:WB, IHC-P
  • 特异性:Human, Rat, Mouse

产品详情

  • 产品名称
    Anti-HP1 alpha (1E8) Mouse antibody
  • 抗体类型
    单克隆
  • 抗体来源
    小鼠
  • 抗体亚型
    小鼠IgG1
  • 抗体描述
    HP1 alpha (1E8) Mouse monoclonal antibody
  • 抗体应用
    WB, IHC-P
  • 应用推荐

    WB: 1/500-1;000

    IHC: 1/100-200

  • 特异性
    Human, Rat, Mouse
  • 制备方法
    Antigen: Purified recombinant protein expressed in E.coli.
  • 组分
    PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
  • 储存方法
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • 背景介绍
    Swiss-Prot Acc.P45973.Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
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