- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB, ICC/IF, FC
- 特异性:Human, Mouse, Rat
产品详情
-
产品名称
Anti-HRH3/Histamine 3 Receptor Rabbit antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
HRH3/Histamine 3 Receptor Rabbit polyclonal antibody
-
抗体应用
WB, ICC/IF, FC
-
应用推荐
WB: 1/1000
ICC/IF: 1/50
FC: 1/20-1/100
-
特异性
Human, Mouse, Rat
-
蛋白别名
HH3R; GPCR97
-
制备方法
Antigen: A synthetic peptide of human HRH3/Histamine 3 Receptor
-
组分
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
储存方法
Store at -20°C. Stable for 12 months from date of receipt.
-
背景介绍
Swiss-Prot Acc.Q9Y5N1.The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.MiscellaneousDoes not bind to cimetidine and tripolidine. Shows modest affinity for thioperamide, imetit, N-alpha-methylhistamine and R--alpha-methylhistamine. Isoform 4 is unable to bind to iodoproxyfan while isoforms 1 and 3 bind it with high affinity.