Anti-IL1RL1 antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB, ELISA
  • 特异性:Mouse IL1RL1 / IL‑1 R4

产品详情

  • 产品名称
    Anti-IL1RL1 antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Rabbit Polyclonal to Mouse IL1RL1
  • 抗体应用
    WB, ELISA
  • 应用推荐

    WB: 5-20 μg/ml

    ELISA: 0.1-0.2 μg/ml

    This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Mouse IL1RL1 / IL‑1 R4.

  • 特异性
    Mouse IL1RL1 / IL‑1 R4
  • 蛋白别名
    ST2, IL‑1 R4, IL33R, DER4, DER4, Fit-1, FIT-1, Il1rl1, IL1RL1, Ly84, MGC32623, St2, ST2L, ST2L, St2-rs1, ST2V, T1, T1, T1/ST2, T1, ST2, DER4, ST2L, ST2V, FIT-1, IL33R, T1, St2, DER4, Ly84, ST2L, Fit-1, T1/ST2, St2-rs1
  • 制备方法
    Produced in rabbits immunized with purified, recombinant Mouse IL1RL1 / IL‑1 R4 . IL1RL1 / IL‑1 R4 specific IgG was purified by Mouse IL1RL1 / IL‑1 R4 affinity chromatography.
  • 组分
    0.2 μm filtered solution in PBS
  • 储存方法
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • 背景介绍
    IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.
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