- 抗体类型:单克隆
- 抗体来源:兔
- 抗体应用:IHC-P
- 特异性:Human CSEN / calsenilin / KCNIP3
产品详情
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产品名称
Anti-KCNIP3 antibody
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抗体类型
单克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Rabbit Monoclonal to Human KCNIP3
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抗体应用
IHC-P
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应用推荐
IHC-P: 1-5 μg/mL
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特异性
Human CSEN / calsenilin / KCNIP3
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蛋白别名
Kv channel interacting protein 3, calsenilin, KCNIP3, CSEN, DREAM, KCHIP3, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, presenilin-binding protein, EF hand transcription factor, potassium channel interacting protein 3, Kv channel interacting protein 3, calsenilin, Kcnip3, RP23-105O13.3, 4933407H12Rik, AI413860, Csen, DREAM, KChIP3, R74849, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, presenilin binding protein, EF hand transcription factor, potassium channel interacting protein 3, CSEN, DREAM, KCHIP3, Csen, DREAM, KChIP3, R74849, AI413860, 4933407H12Rik
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制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human CSEN / calsenilin / KCNIP3 .
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组分
0.2 μm filtered solution in PBS
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储存方法
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
背景介绍
CSEN, also known as calsenilin and KCNIP3, is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. CSEN also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. CSEN binds to the DRE element of genes including PDYN and FOS.