- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB
- 特异性:Human KLK-11 / Kallikrein 11
产品详情
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产品名称
Anti-KLK11/Kallikrein 11 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Rabbit polyclonal to KLK11/Kallikrein 11
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抗体应用
ELISA, WB
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应用推荐
WB: 10-15 μg/mL
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human KLK11. The detection limit for Human KLK11 is 0.00245 ng/well.
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特异性
Human KLK-11 / Kallikrein 11
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蛋白别名
2310015I08Rik, Kallikrein 11, Kallikrein 11, Klk11, KLK11, MGC144345, MGC33060, PRSS20, Prss20, TLSP, TLSP, TLSP, PRSS20, TLSP, Prss20, 2310015I08Rik
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制备方法
Produced in rabbits immunized with purified, recombinant Human KLK11 / Kallikrein 11 (rh KLK-11; NP_006844.1; Met 1-Asn 250). KLK11 specific IgG was purified by human KLK11 affinity chromatography.
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组分
0.2 μm filtered solution in PBS with 5% trehalose
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储存方法
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
背景介绍
kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease and PRSS20, is a member of human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiological functions, which is implicated in carcinogenesis and some with potential that serving as novel biomarkers for ovarian and prostate cancer and other diseases. The KLK11 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Two alternatively spliced forms exist, resulting in 250 (isoform 1) and 282 (isoform 2) amino acid sequences. Isoform 2 is identical to isoform 1, except for an inserted 32 amino acid segment. Isoform 1 is predominantly expressed in brain whereas isoform 2 is preferentially expressed in prostate.