- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:WB, ICC/IF, FC
- 特异性:Human, Mouse, Rat
Anti-MEK2 (5C9) Mouse antibody
产品详情
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产品名称
Anti-MEK2 (5C9) Mouse antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
MEK2 (5C9) Mouse monoclonal antibody
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抗体应用
WB, ICC/IF, FC
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应用推荐
WB: 1/500 - 1/2000
ICC: 1/200 - 1/1000
FC: 1/200 - 1/400
ELISA: 1/10000
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特异性
Human, Mouse, Rat
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制备方法
Antigen: Purified recombinant fragment of human MAP2K2 expressed in E. Coli.
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组分
Ascitic fluid containing 0.03% sodium azide.
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储存方法
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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背景介绍
Swiss-Prot Acc.P36507.MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.
相关服务
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