Anti-Rad51 Rabbit antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:WB, ICC/IF, FC, IP
  • 特异性:Human, Mouse, Rat


  • 产品名称
    Anti-Rad51 Rabbit antibody
  • 抗体类型
  • 抗体来源
  • 抗体亚型
  • 抗体描述
    Rad51 Rabbit polyclonal antibody
  • 抗体应用
    WB, ICC/IF, FC, IP
  • 应用推荐

    WB: 1/2000-1/10000

    ICC/IF: 1/200

    FC: 1/20-1/100

    IP: 1/20

  • 特异性
    Human, Mouse, Rat
  • 蛋白别名
    RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930
  • 制备方法
    Antigen: A synthetic peptide of human Rad51
  • 组分
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • 储存方法
    Store at -20°C. Stable for 12 months from date of receipt.
  • 背景介绍
    Swiss-Prot Acc.Q06609.Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed:28575658). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair (PubMed:26253028).

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