- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IP, IF
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
ATPB antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
ATPB Rabbit Polyclonal antibody. Positive IP detected in mouse heart tissue. Positive WB detected in human heart tissue, HeLa cells, HepG2 cells, mouse liver tissue, rat heart tissue, rat liver tissue. Positive IF detected in HeLa cells. Positive IHC detected in human liver tissue. Observed molecular weight by Western-blot: 56 kDa
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抗体应用
ELISA, WB, IHC, IP, IF
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
ATP5B, ATPB, ATPMB, ATPSB
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制备方法
This antibody was obtained by immunization of ATPB recombinant protein (Accession Number: NM_001686). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
ATP5B, also named as ATPMB and ATPSB, belongs to the ATPase alpha/beta chains family. It is a high affinity HDL receptor for apolipoprotein A1. ATP5B is a subunit of mitochondrial ATP synthase (F1F0 ATP synthase or Complex V ).
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参考文献
- Preuss B, Berg C, Dengjel J, Stevanovic S, Klein R. Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders. Liver international : official journal of the International Association for the Study of the Liver. 32(2):249-57. 2012.
- Hall JA, Kusuma BR, Brandt GE, Blagg BS. Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery. ACS chemical biology. 9(4):976-85. 2014.
- Jokinen R, Lahtinen T, Marttinen P. Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice. Genetics. 200(1):221-35. 2015.
- Richter U, Lahtinen T, Marttinen P, Suomi F, Battersby BJ. Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness. The Journal of cell biology. 211(2):373-89. 2015.