- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
BBS8 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
BBS8 Rabbit Polyclonal antibody. Positive IP detected in HeLa cells. Positive WB detected in mouse testis tissue, human lung tissue, NIH/3T3 cells. Observed molecular weight by Western-blot: 50-52 kDa
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抗体应用
ELISA, WB, IP
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应用推荐
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
BBS8, TPR repeat protein 8, TTC8
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制备方法
This antibody was obtained by immunization of BBS8 recombinant protein (Accession Number: NM_001288781). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
BBS8 (also known as TTC8) is a subunit of BBSome complex which is necessary for ciliary membrane biogenesis. BBS8 localizes specifically to ciliated structures, such as the connecting cilium of the retina and columnar epithelial cells in the lung. Defects in BBS8 cause Bardet-Biedl syndrome type 8 (BBS8), an genetic disorder characterised by retinal degeneration, obesity, polydactyly, cognitive impairment and kidney failure. BBS8 generates two alternatively spliced isoforms. Western blot analysis using this antibody detected a major band around 60 kD in lung tissue.