重组人BVES蛋白

人

大肠杆菌

Met 1 - Asn 36

A DNA sequence encoding the human BVES (NP_671488.1) (Met1-Asn36) was fused with the GST tag at the N-terminus.

> 90 % as determined by SDS-PAGE

The recombinant human BVES/GST chimera consists of 267 amino acids and has a predicted molecular mass of 30.8 kDa. It migrates as an approximately 32.2 KDa band in SDS-PAGE under reducing conditions.

POP1; HBVES; POPEYE DOMAIN CONTAINING 1; BLOOD VESSEL EPICARDIAL SUBSTANCE; RP3-522O2.1; POPEYE DOMAIN-CONTAINING PROTEIN 1; POPEYE 1; BVES; POPDC1; POPEYE PROTEIN 1; MBVES

Blood vessel epicardial substance

Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.

Lyophilized from sterile PBS, pH 7.4.
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

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Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.