- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB, IHC, IF, IP
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
BMI1 antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG2b
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抗体描述
BMI1 Mouse Monoclonal antibody. Positive WB detected in U-937 cells. Positive IP detected in HEK-293 cells. Positive IHC detected in human lymphoma tissue. Positive IF detected in COS-7 cells. Observed molecular weight by Western-blot: 37 kDa
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抗体应用
ELISA, WB, IHC, IF, IP
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:10-1:100
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特异性
Human, Mouse; other species not tested.
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蛋白别名
BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
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制备方法
This antibody was obtained by immunization of BMI1 recombinant protein (Accession Number: NM_005180). Purification method: Protein A purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.