- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:IHC, IP
- 特异性:Human, Rat
产品详情
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产品名称
CASP7 Polyclonal Antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Polyclonal antibody to CASP7
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抗体应用
IHC, IP
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应用推荐
IHC 1:50 - 1:100
IP 1:50 - 1:100 -
特异性
Human, Rat
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蛋白别名
CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3, caspase-7
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制备方法
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human CASP7 (NP_001218.1).
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组分
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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储存方法
Store at -20℃. Avoid freeze / thaw cycles.
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背景介绍
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.