- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, IF, WB
- 特异性:Human; other species not tested.
产品详情
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产品名称
CD33 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
CD33 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Positive IF detected in HepG2 cells. Positive IHC detected in human spleen tissue, human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human testis tissue. Observed molecular weight by Western-blot: 67 kDa
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抗体应用
ELISA, IHC, IF, WB
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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特异性
Human; other species not tested.
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蛋白别名
CD33, CD33 molecule, FLJ00391, gp67, p67, SIGLEC 3, SIGLEC3
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制备方法
This antibody was obtained by immunization of CD33 recombinant protein (Accession Number: NM_001772). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
CD33, aslo referred to as Siglec-3, is a 67-kDa glycosylated transmembrane protein of sialic acid-binding immunoglobulin-like lactic (siglec) family. CD33 expression is restrict to cells of the hematopoietic system. It is expressed on monocytes, myeloid progenitors, granulocytes, mast cells, some T cells. This molecular may mediate cell-to-cell adhesion and act as receptor that inhibits the proliferation of normal and leukemic myeloid cells.
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参考文献
- Dong J, Li J, Liu SM. CD33⁺/p-STAT1⁺ double-positive cell as a prognostic factor for stage IIIa gastric cancer. Medical oncology (Northwood, London, England). 30(1):442. 2013.