CDC20 Polyclonal Antibody
- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB
- 特异性:Human
产品详情
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产品名称
CDC20 Polyclonal Antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Polyclonal antibody to CDC20
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抗体应用
WB
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应用推荐
WB 1:500 - 1:2000
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特异性
Human
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蛋白别名
CDC20, CDC20A, bA276H19.3, p55CDC, cell division cycle 20
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制备方法
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CDC20 (NP_001246.2).
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组分
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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储存方法
Store at -20℃. Avoid freeze / thaw cycles.
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背景介绍
Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!