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- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, IP, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
CKMT1A antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
CKMT1A Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive IP detected in mouse heart tissue. Positive WB detected in rat heart tissue, human colon tissue, human testis tissue, mouse heart tissue, mouse testis tissue. Observed molecular weight by Western-blot: 45 kDa
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抗体应用
ELISA, IHC, IP, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
CKMiMi, CKMT, CKMT1, CKMT1A, FLJ50967, Mia CK, U MtCK
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制备方法
This antibody was obtained by immunization of CKMT1A recombinant protein (Accession Number: NM_001015001). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
CKMT1A(Creatine kinase U-type, mitochondrial) is also named as CKMT and belongs to the ATP:guanido phosphotransferase family. CKMT1A is a nearly identical copy of the CKMT1B gene. Both genes encode an identical CKMT1 protein(PMID:17098888). It reversibly catalyzes the transfer of phosphate between ATP and various phosphogens. It has 2 isoforms produced by alternative splicing with the molecular weight of 47 kDa and 50 kDa.
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参考文献
- Svensson PA, Jernås M, Sjöholm K. Gene expression in human brown adipose tissue. International journal of molecular medicine. 27(2):227-32. 2011.
- Datler C, Grimm S. Reconstitution of CKMT1 expression fails to rescue cells from mitochondrial membrane potential dissipation: implications for controlling RNAi experiments. Biochimica et biophysica acta. 1833(12):2844-55. 2013.
- Enooku K, Nakagawa H, Soroida Y. Increased serum mitochondrial creatine kinase activity as a risk for hepatocarcinogenesis in chronic hepatitis C patients. International journal of cancer. 135(4):871-9. 2014.
- Svensson PA, Lindberg K, Hoffmann JM. Characterization of brown adipose tissue in the human perirenal depot. Obesity (Silver Spring, Md.). 22(8):1830-7. 2014.