CPLX2 antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, WB, IHC
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    CPLX2 antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    CPLX2 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 20kd
  • 抗体应用
    ELISA, WB, IHC
  • 应用推荐

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    921 L, complexin 2, Complexin II, CPLX2, CPX 2, CPX II, CPX2, Hfb1, Synaphin 1
  • 制备方法
    This antibody was obtained by immunization of Peptide (Accession Number: NM_006650). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Neuronal specific complexin 1 (CPLX1) has inhibitory and stimulatory effects on exocytosis by clamping trans-SNARE complexes in a prefusion state and promoting conformational changes to facilitate membrane fusion following cell stimulation. Complexin2 (CPLX2) is a pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals, it is downregulated in schizophrenic patients suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major symptom. This antibody is expected to specifically recogize CPLX2 but not other complexins.
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!