重组食蟹猴CD53蛋白

食蟹猴

人胚胎肾细胞（HEK293）

Glu 107 - Asn 181

A DNA sequence encoding the cynomolgus CD53 (G7NW46) (Glu107-Asn181) was expressed with the Fc region of mouse IgG1 at the N-terminus.

> 95 % as determined by SDS-PAGE

The recombinant cynomolgus CD53 is a disulfide-linked homodimer. The reduced monomer comprises 311 amino acids and has a calculated molecular mass of 34.9 KDa. The apparent molecular mass of it is approximately 44 KDa respectively in SDS-PAGE.

OX-44; LEUKOCYTE SURFACE ANTIGEN CD53; TETRASPANIN-25; CD53 ANTIGEN; CELL SURFACE GLYCOPROTEIN CD53; CELL SURFACE ANTIGEN; CD53 MOLECULE; AI323659; CD53; ANTIGEN MOX44 IDENTIFIED BY MONOCLONAL ANTIBODY MRC-OX44; CD53 GLYCOPROTEIN; TSPAN-25; MOX44; TRANSMEMBRANE GLYCOPROTEIN; CD53 TETRASPAN ANTIGEN; TSPAN25

Tetraspanin

CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.

Lyophilized from sterile PBS, PH 7.4.
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.