重组人DSC2蛋白

人

人胚胎肾细胞（HEK293）

Met 1 - Arg 684

A DNA sequence encoding the extracellular domain (Met 1-Arg 684) of human DSC2 (Q02487-1) was expressed, with a C-terminal polyhistidine tag.

> 75 % as determined by SDS-PAGE

The secreted recombinant human DSC2 (pro form) consists of 668 amino acids and predicts a molecular mass of 75 kDa. As a result of glycosylation, the apparent molecular mass of rhDSC2 is approximately 85 and 100 kDa in SDS-PAGE under reducing conditions, corresponding to the mature and pro form respectively.

DSC2A; ARVD11; DSC3; DGII/III; DG2; DSC2; AW228162; DKFZP686I11137; CDHF2; DSC2B

Desmocollin-2

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

Lyophilized from sterile PBS, pH 7.4
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.