- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IF
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
DLG1 antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
DLG1 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human heart tissue. Positive WB detected in mouse lung tissue, HeLa cells. Observed molecular weight by Western-blot: 120 kDa or 130-140 kDa
-
抗体应用
ELISA, WB, IHC, IF
-
应用推荐
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
IF: 1:50-1:500
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
Disks large homolog 1, dJ1061C18.1.1, DKFZp761P0818, DKFZp781B0426, DLG1, DLGH1, hdlg, SAP 97, SAP97, Synapse assOCiated protein 97
-
制备方法
This antibody was obtained by immunization of Peptide (Accession Number: NM_004087). Purification method: Antigen affinity purified.
-
组分
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
DLG1, also naemd as SAP97, hDlg and DLGH1, belongs to the MAGUK family. It is essential multidomain scaffolding protein required for normal development. DLG1 may play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. It regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. DLG1 is a functional regulator of Kv1.5 channel. The DLG1-MPP7 complex promotes epithelial cell polarity and tight junction formation. The antibody is specific to DLG1.
-
参考文献
- Westland R, Verbitsky M, Vukojevic K. Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney. Kidney international. 88(6):1402-1410. 2015.