重组人DYRK3蛋白

产品详情

  • 产品名称
    重组人DYRK3蛋白
  • 蛋白种属
    人
  • 表达宿主
    杆状病毒 - 昆虫细胞
  • Unitprot ID
    O43781
  • 蛋白序列
    Met 1 - Ser 588
  • 克隆构建
    A DNA sequence encoding the human DYRK3 isoform 1 (O43781-1) (Met 1-Ser 588) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
  • 蛋白纯度
    > 85 % as determined by SDS-PAGE
  • 蛋白活性
    The specific activity was determined to be 22 nmol/min/mg using synthetic DYRKtide peptide (RRRFRPASPLRGPPK) as substrate.
  • 分子量
    The recombinant human DYRK3/GST chimera consists of 825 amino acids and has a calculated molecular mass of 93.5 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.
  • 蛋白别名
    HYAK3-2; REDK; RP11-343H5.2; DYRK3; BC006704; DYRK5; RED
  • 蛋白全名
    Dual specificity tyrosine-phosphorylation-regulated kinase 3
  • 蛋白描述
    Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
  • 发货形式
    Supplied as sterile 20mM Tris, 500mM NaCl, 0.5mM PMSF, 10% gly, pH 8.0
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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