E2F3 Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:WB
  • 特异性:Mouse, Rat

产品详情

  • 产品名称
    E2F3 Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to E2F3
  • 抗体应用
    WB
  • 应用推荐
    WB 1:500 - 1:2000
  • 特异性
    Mouse, Rat
  • 蛋白别名
    E2F3, E2F-3, transcription factor E2F3
  • 制备方法
    Antigen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human E2F3 (NP_001230005.1).
  • 组分
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 储存方法
    Store at -20℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!