- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC
- 特异性:human, rat; other species not tested.
产品详情
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产品名称
EXOSC5 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
EXOSC5 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells, HEK-293 cells, HeLa cells, Raji cells, rat kidney tissue. Positive IHC detected in human breast cancer. Observed molecular weight by Western-blot: 28-30 kDa
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抗体应用
ELISA, WB, IHC
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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特异性
human, rat; other species not tested.
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蛋白别名
EXOSC5, p12B, exosome component 5, RRP46, hRrp46p
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制备方法
This antibody was obtained by immunization of EXOSC5 recombinant protein (Accession Number: NM_020158). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
CML28 is a component of the human exosome, which is a multiprotein complex involved in the 3′ processing and degradation of RNA [PMID:12359762]. CML28 is a novel 28 kDa TAA identified by serological analysis of cDNA expression libraries (SEREX) screening of a chronic myeloid leukemia (CML) cDNA expression library. As a potential target for tumor-specific immunotherapy, CML28 is superior to other known TAAs characterized by its broader spectrum expression in tumor cells and stricter expression in normal tissues [PMID:16815301].