- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
FBX15 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
FBX15 Rabbit Polyclonal antibody. Positive WB detected in A2780 cells, mouse ovary tissue. Observed molecular weight by Western-blot: 55kd
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
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特异性
Human, Mouse; other species not tested.
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蛋白别名
F box only protein 15, F box protein 15, FBX15, FBXO15
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制备方法
This antibody was obtained by immunization of FBX15 recombinant protein (Accession Number: XM_017025604). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. The F-box proteins are divided into 3 classes: FBWs containing WD-40 domains, FBLs containing leucine-rich repeats, and FBXs containing either different protein-protein interaction modules or no recognizable motifs. FBOX15 (or FBX15) belongs to the FBXs class, and 2 isoforms produced by alternative splicing has been described. This antibody is expected detect both isoforms.