重组人B3GAT3蛋白

产品详情

  • 产品名称
    重组人B3GAT3蛋白
  • 蛋白种属
  • 表达宿主
    大肠杆菌
  • Unitprot ID
  • 蛋白序列
    Glu 72 - Val 335
  • 克隆构建
    A DNA sequence encoding the human B3GAT3 (NP_036332.2) (Glu72-Val335) was expressed with a polyhistidine tag at the N-terminus.
  • 蛋白纯度
    > 85 % as determined by SDS-PAGE
  • 分子量
    The recombinant human B3GAT3 consists of 282 amino acids and predicts a molecular mass of 31.5 KDa. It migrates as an approximately 33 KDa band in SDS-PAGE under reducing conditions.
  • 蛋白别名
    SQV-8-LIKE PROTEIN; UDP-GLCUA:GAL BETA-1; GLCAT-I; GLCUAT-I; 3-GLUCURONYLTRANSFERASE 3 (GLUCURONOSYLTRANSFERASE I); GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3; 2810405M13RIK; 3-GAL-R GLUCURONYLTRANSFERASE; GLUCURONOSYLTRANSFERASE I; GLCATI; GLUCURONYLTRANSFERASE I; BETA-1; B3GAT3
  • 蛋白全名
    Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
  • 蛋白描述
    Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.
  • 发货形式
    Lyophilized from sterile PBS, pH 7.4.
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    Please contact us for more information.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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