- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB, IHC
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
GEFT antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG2a
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抗体描述
GEFT Mouse Monoclonal antibody. Positive WB detected in mouse skeletal muscle tissue, human brain tissue, mouse brain tissue, rat brain tissue, rat skeletal muscle tissue. Positive IHC detected in human heart tissue, human brain tissue. Observed molecular weight by Western-blot: 53 kDa, 63 kDa
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抗体应用
ELISA, WB, IHC
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
GEFT, p63RhoGEF, RhoA/RAC/CDC42 exchange factor
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制备方法
This antibody was obtained by immunization of GEFT recombinant protein (Accession Number: NM_133483). Purification method: Protein A purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
GEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis.