- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IF
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
GLRX3 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
GLRX3 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue, human ovary tumor tissue. Positive IF detected in Hela cells. Positive WB detected in human brain tissue, Jurkat cells. Observed molecular weight by Western-blot: 37kd
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抗体应用
ELISA, WB, IHC, IF
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
bA500G10.4, FLJ11864, GLRX3, GLRX4, Glutaredoxin 3, GRX3, GRX4, PICOT, PKC theta interacting protein, PKCq interacting protein, Thioredoxin like protein 2, TXNL2, TXNL3
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制备方法
This antibody was obtained by immunization of GLRX3 recombinant protein (Accession Number: BC014372). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals(PMID:20226171). Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially(PMID:19797004).
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参考文献
- Lee EJ, In KH, Kim JH. Proteomic analysis in lung tissue of smokers and COPD patients. Chest. 135(2):344-52. 2009.