GZMA Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB, IF
  • 特异性:Human, Mouse, Rat

产品详情

  • 产品名称
    GZMA Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to GZMA
  • 抗体应用
    WB, IF
  • 应用推荐
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • 特异性
    Human, Mouse, Rat
  • 蛋白别名
    GZMA, CTLA3, HFSP, granzyme A
  • 制备方法
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-262 of human GZMA (NP_006135.1).
  • 组分
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 储存方法
    Store at -20℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
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