- Unitprot ID:P08758
A DNA sequence encoding the Human ANXA5/ANX5/ENX2/PP4 Ala2-Asp320 is expressed.
>95% as determined by SDS-PAGE.
ANX5; ENX2; PP4
Annexin A5 (ANXA5) is a member of the annexin family of calcium-dependent phospholipid binding proteins. ANXA5 is an anticoagulant protein by acting as an indirect inhibitor of the thromboplastin-specific complex. ANXA5 is also a protein kinase C and phospholipase A2 inhibitor. It participate in inflammation, cellular signal transduction, growth and differentiation. ANXA5 binding to phosphatidylserine and sulfatide to regulates coagulability in the blood stream. It also protects sinsuoidal endothelial cells from ischemia reperfusion damage. ANXA5 is important for normal CFTR chloride channel activity.
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 1mM DTT, 10% Glycerol, pH 8.0.
<1.0 EU per μg protein as determined by the LAL method.
Store at <-20°C, minimize freeze-thaw cycles.