重组人CPB1蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human CPB1/CPB/PCPB His16-Tyr417 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

CPB; PCPB

carboxypeptidase B1(CPB1)

Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.

Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

<1.0 EU per μg protein as determined by the LAL method.

Store at <-20°C, minimize freeze-thaw cycles.