重组人CTGF蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human CTGF/CCN2/HCS24/IGFBP8 Glu27-Ala180 is expressed.

>95% as determined by SDS-PAGE.

CCN2; HCS24; IGFBP8

connective tissue growth factor(CTGF)

CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).

Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.