重组人IFNA7蛋白

人

酵母

A DNA sequence encoding the human IFNA7 (NP_066401.2) (Cys24-Asp189) was expressed with a polyhistidine tag at the C-terminus.

> 95 % as determined by SDS-PAGE.

Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus. The ED₅₀ for this effect is 3.0-15.0pg/mL.

The recombinant human IFNA7 consists of 176 amino acids and predicts a molecular mass of 21 kDa.

IFN-alphaJ,IFNA-J

Interferon alpha-7

Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFN are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons.

Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.

Please contact us for more information.

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.