重组人IFNGR1蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human IFNGR1 Glu18-Ser245 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

interferon gamma receptor 1(IFNGR1)

Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Store at <-20°C, minimize freeze-thaw cycles.