重组人KLK10蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human KLK10/NES1/PRSSL1 Ala31-Asn276 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

NES1; PRSSL1

kallikrein related peptidase 10(KLK10)

Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.

<1.0 EU per μg protein as determined by the LAL method.

Store at <-20°C, minimize freeze-thaw cycles.