重组人SIKE1蛋白

产品详情

  • 产品名称
    重组人SIKE1蛋白
  • 蛋白种属
    人
  • 表达宿主
    大肠杆菌
  • Unitprot ID
    Q9BRV8
  • 蛋白序列
    112-211
  • 克隆构建
    A DNA sequence encoding the human SIKE1 (NP_001095866.1) 112-211 aa was fused with the polyhistidine tag
  • 蛋白活性
    Not tested.
  • 蛋白别名
    SIKE
  • 蛋白全名
    Suppressor of IKBKE 1
  • 蛋白描述
    Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways. {PubMed:16281057}.
  • 发货形式
    Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 300 mM Imidazole, pH 8.0). Trehalose (5-8%) and mannitol (5-8%) protectants were added before lyophilization.
  • 内毒素
    Please contact the lab for more information.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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