重组人VPS36蛋白
- 蛋白种属:人
- 表达宿主:大肠杆菌
- Unitprot ID:Q86VN1
产品详情
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产品名称
重组人VPS36蛋白
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蛋白种属
人
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表达宿主
大肠杆菌
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Unitprot ID
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蛋白序列
1-386
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克隆构建
A DNA sequence encoding the human VPS36 (NP_057159.2) 1-386 aa was fused with the polyhistidine tag
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蛋白活性
Not tested.
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蛋白别名
C13orf9; EAP45
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蛋白全名
Vacuolar protein-sorting-associated protein 36
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蛋白描述
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
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发货形式
Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 300 mM Imidazole, pH 8.0). Trehalose (5-8%) and mannitol (5-8%) protectants were added before lyophilization.
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内毒素
Please contact the lab for more information.
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保存条件
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
重组蛋白定制服务:
纽普生物(NovoPro)提供大肠杆菌、哺乳细胞、昆虫细胞和酵母细胞重组蛋白定制服务
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!