重组大鼠IL7蛋白

大鼠

大肠杆菌

Asp 26 - Ile 154

A DNA sequence encoding the rat IL7 (Q91Y32) (Asp26-Ile154) was expressed and purified with an initial Met.

> 90 % as determined by SDS-PAGE

Measured by its ability to bind rat IL7R-mFc (Cat:501881) in a functional ELISA.

The recombinant rat IL7 consists of 130 amino acids and has a predicted molecular mass of 15 kDa. The apparent molecular mass of the recombinant protein is approximately 17 kDa in SDS-PAGE under reducing conditions.

HLB368; INTERLEUKIN 7; IL7; A630026I06RIK; IL-7

Interleukin-7

IL7, also known as interleukin 7, is a hematopoietic growth factor which belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.

Lyophilized from sterile PBS, pH 7.4.
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

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Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.