KANK2 Polyclonal Antibody

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  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:WB
  • 特异性:Human, Mouse

产品详情

  • 产品名称
    KANK2 Polyclonal Antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    Polyclonal antibody to KANK2
  • 抗体应用
    WB
  • 应用推荐
    WB 1:500 - 1:2000
  • 特异性
    Human, Mouse
  • 蛋白别名
    KANK2, ANKRD25, MXRA3, PPKWH, SIP, KN motif and ankyrin repeat domains 2
  • 制备方法
    Antigen: A synthetic peptide of human KANK2
  • 组分
    PBS with 0.02% sodium azide, pH7.3.
  • 储存方法
    Store at 4℃. Avoid freeze / thaw cycles.
  • 背景介绍
    Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3. Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria. Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis. Involved in the negative control of vitamin D receptor signaling pathway. Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway. May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney. Through the Rho signaling pathway may also regulate cell proliferation (By similarity).
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