重组人LILRB2蛋白

产品详情

  • 产品名称
    重组人LILRB2蛋白
  • 蛋白种属
  • 表达宿主
    人胚胎肾细胞(HEK293)
  • Unitprot ID
  • 蛋白序列
    Met 1 - Val 461
  • 克隆构建
    A DNA sequence encoding the human LILRB2 (AAH36827.1) (Met1-Val461) was expressed with a polyhistidine tag at the C-terminus.
  • 蛋白纯度
    > 90 % as determined by SDS-PAGE
  • 分子量
    The recombinant human LILRB2 consists of 451 amino acids and predicts a molecular mass of 49.2 KDa. It migrates as an approximately 66 KDa band in SDS-PAGE under reducing conditions.
  • 蛋白别名
    IG-LIKE TRANSCRIPT 4; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR 2; LILRA6; XXBAC-BCX105G6.12-005; ILT-4; MEMBER 6; LIR-2; MIR10; SUBFAMILY B (WITH TM AND ITIM DOMAINS); SUBFAMILY A (WITH TM DOMAIN); EUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR; CD85 ANTIGEN-LIKE FAMILY MEMBER D; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2 SOLUBLE ISOFORM; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR; CD85D; MIR-10; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2; ILT4; IMMUNOGLOBULIN-LIKE TRANSCRIPT 4; LIR2; MONOCYTE/MACROPHAGE IMMUNOGLOBULIN-LIKE RECEPTOR 10; MEMBER 2; LILRB2
  • 蛋白全名
    Leukocyte immunoglobulin-like receptor subfamily B member 2
  • 蛋白描述
    ILT4, also known as LILRB2, is a member of the the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
  • 发货形式
    Lyophilized from sterile PBS, pH 7.4
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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