- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IP, FC
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
LIFR antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
LIFR Rabbit Polyclonal antibody. Positive IP detected in mouse skeletal muscle tissue. Positive WB detected in human skeletal muscle tissue, mouse skeletal muscle tissue. Positive FC detected in HeLa cells. Positive IHC detected in human skeletal muscle tissue, human kidney tissue, human placenta tissue. Observed molecular weight by Western-blot: 190 kDa
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抗体应用
ELISA, WB, IHC, IP, FC
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:500-1:5000
IHC: 1:20-1:200
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特异性
Human, Mouse; other species not tested.
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蛋白别名
CD118, FLJ98106, FLJ99923, LIF R, LIF receptor, LIFR, SJS2, STWS, SWS
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制备方法
This antibody was obtained by immunization of LIFR recombinant protein (Accession Number: XM_011514040). Purification method: Antigen Affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
LIFR, also known as CD118, is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family which affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M (PMID: 8999038). LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway (PMID: 23001183).