- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
Mast Cell Chymase antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Mast Cell Chymase Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, human heart tissue, human placenta tissue, MCF7 cells. Positive IP detected in mouse heart tissue. Observed molecular weight by Western-blot: 27-30 kDa
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抗体应用
ELISA, WB, IP
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
Alpha chymase, chymase, chymase 1, mast cell, CMA1, CYH, CYM, Mast Cell Chymase, Mast cell protease I, Mcpt 5, Mcpt5, MCT1
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制备方法
This antibody was obtained by immunization of Mast Cell Chymase recombinant protein (Accession Number: NM_001836). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Mast Cell Chymase, also named as CYH, CYM and CMA1, belongs to the peptidase S1 family and Granzyme subfamily. It is the major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. CMA1 maybe a target for cardiovascular disease therapies.
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参考文献
- Baumann A, Gönnenwein S, Bischoff SC. The circadian clock is functional in eosinophils and mast cells. Immunology. 140(4):465-74. 2013.
- Smith ET, Perry ET, Sears MB, Johnson DA. Expression of recombinant human mast cell chymase with Asn-linked glycans in glycoengineered Pichia pastoris. Protein expression and purification. 102:69-75. 2014.
- Shi H, Jiang H, Wang L. Overexpression of monocarboxylate anion transporter 1 and 4 in T24-induced cancer-associated fibroblasts regulates the progression of bladder cancer cells in a 3D microfluidic device. Cell cycle (Georgetown, Tex.). 14(19):3058-65. 2015.