重组小鼠F10蛋白

产品详情

  • 产品名称
    重组小鼠F10蛋白
  • 蛋白种属
    小鼠
  • 表达宿主
    人胚胎肾细胞（HEK293）
  • Unitprot ID
    O88947
  • 克隆构建
    A DNA sequence encoding the Mouse F10 Gly21-Asn481 is expressed with a 6His tag at the C-terminus.
  • 蛋白纯度
    >95% as determined by SDS-PAGE.
  • 蛋白全名
    coagulation factor X(F10)
  • 蛋白描述
    Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin K-dependent plasma protease that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. The two chains of F10 are formed from a single-chain precursor by the excision of two Arg residues. A single-chain precursor is initially synthesized in the liver. The light and heavy chains are linked together by disulfide bonds. The light chain contains a Gla and two EGF-like domains. The heavy chain corresponds to the serine protease domain. It can form a heterodimer with SERPINA5.
  • 发货形式
    Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl and 1mM CaCl2 pH7.5..
  • 内毒素
    <1.0 EU per μg protein as determined by the LAL method.
  • 保存条件
    Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
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